Governance

National Consortium (Steering) Committee:

  • Coordinating Principal Investigator and Director: Lyn March (NSW)
  • Sponsor: University Sydney Representative
  • Consumer Advocacy: Arthritis Australia Representative
  • Peak Body: Australian Rheumatology Association (ARA) Representative
  • State Node Primary Custodians:
    • Lyn March (University of Sydney and NSW Statewide Biobank, NSW)
    • Jane Munro (Murdoch Children’s Research Institute, VIC)
    • Catherine Hill (Queen Elizabeth Hospital, SA)
    • Mihir Wechalekar (Flinders Medical Centre, SA)
    • Helen Keen (Fiona Stanley Hospital, WA)
    • Ranjeny Thomas (University of Queensland, QLD)
    • Tony Kenna (Queensland University of Technology, QLD)
    • Chandima Perera (Canberra Hospital, ACT)

* Includes a Chairperson agreed by all

National Operations Management

  • National Project Officer: Tom Lynch
  • National Juvenile Arthritis Project Officer: Fiona Howard
  • National Database Manager: Vibhasha Chand
  • Executive Administrator: Marita Cross
  • Clinical Trial Coordinator: Jie Yi
  • Lead Laboratory Scientist: Meilang Xue

National Access Committee

  • Sponsor Representative
  • A3BC Node Custodian Representatives (excl. any COI)
  • Australian Rheumatology Association (ARA) Representative
  • Consumer Advocacy Group Representative
  • A3BC-ARAD patient research partner(s)
  • National Biobank Director

* Includes a Chairperson agreed by all

International Scientific and Strategic Advisory

National

  1. Clinical – Adult
  2. Clinical – Paediatric
  3. Biobanking and Multi-omics
  4. Registries and Epidemiology
  5. Analytics – Traditional and AI
  6. Genetic Counselling
  7. Health Policy

International

  1. Rheumatology Precision Medicine
  2. Adult Rheumatologist and Precision Medicine Research
  3. Paediatric Rheumatologist and Precision Medicine Research
  4. International Large-scale Biobanking
  5. Health Data Informatics and Research

* Includes a Chairperson agreed by all

Ethical Legal and Social Implications Committee

  • Independent biobank ethics
  • Independent bio-legal
  • Independent social scientist
  • Semi-independent consumer advocacy
  • A3BC National Director (coordinator only)

* Includes a Chairperson agreed by all

Key governance information:

  • The overarching A3BC governance philosophy is one of collaboration and cooperation to emphasize capacity building and career development for the future
  • The A3BC is owned and operated as an unincorporated joint venture between a consortium of leading researcher, biobank and data custodians. The A3BC Consortium Committee, guided by their Terms of Reference provides assistance, oversight and guidance on matters including:
    • annual plans and priorities
    • determining national policies
    • monitoring risks and timelines
    • preliminary access applications
    • harmonising / improving practice
    • beneficial relationship building
    • cooperation between nodes
    • training opportunities
    • intellectual property
    • raising awareness
    • funding options
    • budgeting
  • Decision-making by the Consortium Committee is guided by related independent and expert advice from the ELSI and ISSA groups.
  • The national Access Committee provides central review and approval for research applications to access the A3BC.
    • Where a collection is NSW Health grant funded, the NSW Health Statewide Biobank Access Committee is used in conjunction with the A3BC Access Committee.
  • The core operational structure of the A3BC consists of dedicated local and National components to ensure local harmonisation and collaborative national management.
  • Biobank node custodianship is typically shared by a local Primary (a local clinician Principal Investigator) and Deputy (a local Biobank/Lab Manager) custodian per node to prevent COI and ensure strong clinical, research and operational knowledge in decision-making. The Primary custodian has final decision making powers.
  • A3BC funding is managed by the University of Sydney, who are ACNC registered (capable to take donations) and an authorised entity to manage Commonwealth grant funds.